Close

Clinical Focus Areas

ACROBATIC has three Clinical Focus Areas (CFAs) that are relevant across all 11 Danish Multidisciplinary Cancer Groups (DMCGs), covering prehabilitation, surgical innovation, and survivorship. All the projects (work packages) under ACROBATIC are covered by one or more of the CFAs.

Each CFA is headed by a leader, who is responsible for facilitating the initiation of national studies and trials through organization of CFA workshops and meetings, where knowledge sharing and collaboration across discipline and cancer type can flourish.

CFA1: Prehabilitation and preoperative risk assessment

  • Increased and focused optimization before surgery
  • Develop new algorithms for selecting the right patient for the right operation

Leader

Bente Thoft Jensen, PhD

Department of Urology, Aarhus University Hospital

Work Packages

WP 1.1: Multimodal Prehabilitation in Frail Colon Cancer Patients

WP leaders

Katrine J Emmertsen, MD, PhD, Department of Surgery, Regional Hospital Randers, Denmark
Ismail Gögenur, MD, DMSc, Professor, Centre for Surgical Science, Zealand University Hospital, Denmark

 

DMCG

Danish Colorectal Cancer Group

 

Participating institutions

Department of Surgery, Regional Hospital Randers
Dept. of Surgery, Zealand, Denmark University Hospital, Køge
Department of Surgery, Slagelse Hospital, Denmark
Department of Surgery, Viborg Regional Hospital, Denmark
Department of Surgery, Regional Hospital West Jutland, Herning, Denmark
Department of Surgery, Regional Hospital Horsens, Denmark
Department of Surgery, Vejle Hospital, part of Lillebaelt Hospital, Denmark
Department of Surgery, Aalborg University Hospital, Denmark
Department of Surgery, Aarhus University Hospital. Denmark
Department of Surgery, North Zealand Hospital Hillerød, Denmark
Department of Geriatrics at Aarhus University Hospital. Denmark
Steno Diabetes Center Aarhus, Aarhus University Hospital, Denmark
Danish Center for Health Economics, University of Southern Denmark, Denmark

 

Status: Incorporated into WP 1.7

WP 1.2: COMPETENCE - Perioperative Comprehensive Geriatric Assessment and tailored intervention in older, frail patients with muscle invasive bladder cancer scheduled for radical cystectomy

WP leader

Bente Thoft Jensen, Ph.D., Department of Urology, Aarhus University Hospital, Denmark

 

DMCG

Danish Bladder Cancer Group

 

Participating institutions
Department of Urology at all five University Hospitals performing radical cystectomies in Denmark:
Aalborg University Hospital
Aarhus University Hospital
Odense University Hospital
Copenhagen University Hospital, Rigshospitalet
Herlev University Hospital

 

Status: Recruiting

WP 1.3: FRAGINOC: The impact of FRAilty screening and Geriatric assessment and INtervention in older patients with epithelial Ovarian Cancer.

WP leader

Tine Henrichsen Schnack, associate professor, PhD, Department of Gynecology, Odense University Hospital, Denmark

 

DMCG

Danish Gynecologic Cancer Group

 

Participating institutions
Department of Gynecology, Odense University Hospital, Denmark 
Department of Gynecology, Copenhagen University Hospital, Rigshospitalet, Denmark
Department of Gynecology, Roskilde University Hospital, Denmark
Department of Oncology, Odense University Hospital, Denmark
Department of Oncology, Copenhagen University Hospital, Rigshospitalet, Denmark
Department of Oncology, Roskilde University Hospital, Denmark
Department of Oncology, Herlev University Hospital, Denmark
Department of Geriatric, Odense University Hospital, Denmark
Department of Geriatric, Herlev University Hospital, Denmark

 

Status: Recruiting

WP 1.4: RESTORE: Rehabilitative Exercise to elevate function for Surgical ineligible patienTs with nOn Small cell lung cancer to achieve possible cuRative surgEry.

WP leader

Morten Quist, Ph.D., PT., Rigshospitalet, Copenhagen University Hospital, Denmark

 

DMCG

Danish Lung Cancer Group

 

Participating institutions
Department of Cardio-Thoracic Surgery, Copenhagen University Hospital, Rigshospitalet, Denmark
Department of Cardio-Thoracic Surgery, Aalborg University Hospital, Denmark
Department of Cardio-Thoracic Surgery, Aarhus University Hospital, Denmark
Department of Cardio-Thoracic Surgery, Odense University Hospital, Denmark

 

Status: Expected start August 2024

WP 1.5: A randomized trial of enhanced recovery after radical prostatectomy

WP leader

Mads Hvid Aaberg Poulsen, consultant, associate professor, PhD, Department of Urology, Odense University Hospital, Denmark

 

DMCG

Danish Prostate Cancer Group

 

Participating institutions

Department of Urology, Odense University Hospital, Denmark
Department of Urology, Roskilde University Hospital, Denmark

 

Status: Pending

WP 1.7: AI-Driven Personalized Perioperative Management in Colorectal Cancer: A Randomized Controlled Clinical Trial - The AIDPRO-CRC trial

WP leader

Ismail Gögenur, MD, DMSc, Professor, Centre for Surgical Science, Zealand University Hospital

 

DMCGs

Danish Colorectal Cancer Group
Danish Renal Cancer Group
Danish Lung Cancer Group
Danish Gynecologic Cancer Group
Danish Prostate Cancer Group
Danish Bladder Cancer Group

 

Coordinating institution

Centre for Surgical Science, Zealand University Hospital, Denmark

 

Status: Recruiting

WP 1.8: The lived experience of physical prehabilitation among older women with advanced ovarian cancer and their families.

WP leader

Eva Jespersen, Ph.D, Associate professor, Department of Gynecology, Odense University Hospital and Svendborg Sygehus, Denmark

 

DMCGs

Danish Gynecological Cancer Group

 

Participating institutions

Department of Gynecology, Odense University Hospital, Denmark.

Department of Gynecology, Roskilde Hospital, Denmark.

Department of Gynecology, Herlev and Gentofte Hospital, Denmark

Department of Gynecology,  Rigshospitalet, Denmark.

 

Status: Pending

CFA2: Surgical innovation and technique

  • Developing of innovative methods to optimize the surgical techniques
  • Establish a national surgical data collection system for robotic surgery
  • Creation of a national platform for experimental cancer surgery
  • Repurposing of novel surgical techniques and innovation across DMCGs derived from the cross- and inter-disciplinary collaboration

Leader

Thomas Baad-Hansen, MD, PhD

Professor, Consultant Orthopaedic Surgeon

Department of Othopaedic Surgery, Aarhus University Hospital, Denmark

Work Packages

WP 2.1: Surgical Data Vault - Improved surgical proficiency by linking robotic data to the operation

WP leader

Thiusius Rajeeth Savarimuthu M.Sc.Eng, PhD, Professor, Maersk Mc-Kinney Moller Institute, University of Southern Denmark, Denmark

 

DMCGs

All DMCGs performing robotic surgery

 

Participating institutions

Sub-specialities within each DMCG will be involved in a national data collection project

 

Status: Ongoing

WP 2.2: Quality of Life After primary TORS vs IMRT. "The QoLATI study” for patients with early-stage oropharyngeal squamous cell carcinoma: A Randomized National Trial

WP leader

Christian von Buchwald, Professor, DMSc, Department of Otorhinolaryngology, Head and Neck Surgery and Audiology, Rigshospitalet, Denmark

 

DMCG

Danish Head and Neck Cancer Group

 

Participating institutions

Department of Otorhinolaryngology, Head and Neck Surgery, Rigshospitalet, Denmark
Department of Otorhinolaryngology, Head and Neck Surgery, Odense University Hospital, Denmark
Department of Otorhinolaryngology, Head and Neck Surgery, Aarhus University Hospital, Denmark

 

Status: Recruiting

WP 2.3: Economic Evaluation of Transoral Robotic Surgery versus Intensity Modulated Radiotherapy for Early Oropharyngeal Squamous Cell Carcinoma

WP leader

Thomas Kjærgaard, MD, PhD, Departmet of Otorhinolaryngology – Head & Neck Surgery, Aarhus University Hospital, Denmark

 

DMCG

Danish Head and Neck Cancer Group

 

Participating institutions

Department of Otorhinolaryngology, Head and Neck Surgery, Rigshospitalet, Denmark
Department of Otorhinolaryngology, Head and Neck Surgery, Odense University Hospital, Denmark

 

Status: Ongoing

WP 2.4: The Introduction of Salvage Robot-Assisted Radical Prostatectomy in Denmark

WP leaders

Mads Hvid Aaberg Poulsen, consultant, associate professor, Department for Urology, Odense University Hospital, Denmark
Michael Borre, Professor, Department of Urology Aarhus University Hospital, Denmark

 

DMCG

Danish Prostate Cancer Group

 

Participating institutions

Department of Urology, Odense University Hospital, Denmark
Depatment of Urology, Herlev Hospital, Denmark
Department of Urology, Aalborg University Hospital, Denmark

 

Status: Recruiting

WP 2.5: Better surgical palliation of patients with incurable cancer

WP leader

Hans Bjarke Rahr, MD DMSc, Professor, Deptartment of Surgery, part of Lillebaelt Hospital, Vejle Hospital, Denmark

 

DMCGs

TBA

 

Participating institutions

TBA

 

Status: TBA

WP 2.6: Palliative Pelvic Exenteration for Alleviating Symptoms in Cancer Patients

WP leader

Jonas Amstrup Funder, consultant, associate professor, PhD, Department of Surgery, Sygehus Lillebælt

 

DMCGs

Danish Colorectal Cancer Group
Danish Anal Cancer Group
Danish Gynecological Cancer Group
Danish Sarcoma Group

 

Participating institutions

Deptartment of Surgery, Aarhus University Hospital, Denmark
Department of Gynaecology, Aarhus University Hospital, Denmark

Danish Center for Health Economics (DaCHE), University of Southern Denmark

Department of Colorectal Surgery, St. Vincents University Hospital, Dublin.

 

Status: Pending

WP 2.8: SENTIVUC: Optic-guided Sentinel Node Mapping in patients with vulva cancer

WP leader

Ligita Paskeviciute Frøding, MD, Department of Gynecology, Copenhagen University Hospital, Rigshospitalet, Denmark

 

DMCG

Danish Gynecologic Cancer Group

 

Participating institutions

The two national centres for vulva cancer:
Department of Gynecology, Copenhagen University Hospital, Rigshospitalet, Denmark
Department of Gynecology, Aarhus University Hospital, Denmark

 

Status: Recruiting

WP leaders

Jens Ahm Sørensen MD, PhD, Professor, Consultant Plastic Surgeon, Department of Plastic Surgery, Odense University Hospital, Odense, Denmark
Tine Engberg Damsgaard MD, PhD, MRBS, Professor, Consultant Plastic Surgeon, Deptartment of Plastic Surgery, part of Lillebaelt Hospital, Vejle Hospital, Denmark

 

DMCG

Danish Breast Cancer Group

 

Participating institutions

Department of Plastic Surgery, Odense University Hospital, Odense, Denmark

Deptartment of Plastic Surgery, part of Lillebaelt Hospital, Vejle Hospital, Denmark

 

Status: Recruiting

WP 2.10: Reduction of positive margins and local recurrence in malignant musculoskeletal tumors – repurposing established technology for novel applications

WP leaders

Tine Engberg Damsgaard MD, PhD, MRBS, Professor, Consultant Plastic Surgeon, Department of Plastic Surgery, part of Lillebaelt Hospital, Vejle Hospital, Denmark

Thomas Baad-Hansen, Professor, Sarcoma division, Aarhus University Hospital, Aarhus, Denmark

 

DMCG

Danish Sarcoma Group

 

Participating institutions

Department of Orthopaedic Surgery (Section for Tumor Surgery), Aarhus University Hospital, Denmark
Department of Orthopaedic Surgery, Copenhagen University Hospital (Rigshospitalet), Copenhagen, Denmark
Department of Plastic Surgery, part of Lillebaelt Hospital, Vejle Hospital, Denmark

 

Status: Pending

WP 2.11: Improving sarcoma survival - implementing 3D print technology in complex sarcoma surgery

WP leader

Thomas Baad-Hansen, Professor, Sarcoma division, Aarhus University Hospital, Aarhus, Denmark

 

DMCG

Danish Sarcoma Group

Participating institutions

 

Sarcoma division, Aarhus University Hospital, Denmark
Sarcoma division, Rigshospitalet, Copenhagen, Denmark

 

Status: Ongoing

WP 2.12: Breast Cancer: 3D-printing of tumors and planning of breast conserving surgery

WP leader

Marianne Djernes Lautrup, consultant, associate professor, PhD, Department of Plastic and Breast Surgery, Aarhus University Hospital, Denmark

 

DMCG

Danish Breast Cancer Group

 

Participating institution

Deptartment of Plastic and Breast Surgery, Aarhus University Hospital, Denmark

 

Status: Inactive

WP 2.13: DBCG RT RECON trial: Delayed-immediate versus delayed breast reconstruction in early breast cancer patients treated with mastectomy and adjuvant loco-regional radiation therapy: A multicenter randomized clinical trial

WP leader

Tove Filtenborg Tvedskov, PhD, DMSc, consultant, associate professor, Deptartment of Breast Surgery, Herlev/Gentofte Hospital and Rigshospitalet, Denmark

 

DMCG

Danish Breast Cancer Group

 

Participating institutions

Deptartment of Breast Surgery, Herlev/Gentofte Hospital and Rigshospitalet, Denmark

Department of Plastic Surgery, Copenhagen University Hospital, Denmark
Department of Experimental Clinical Oncology, Aarhus University Hospital, Denmark
Department of Plastic and Breast Surgery, Aarhus University Hospital, Denmark

 

Status: Recruiting

WP 2.14: Planning of surgery in the breast after NACT - how much to excise?

WP leaders

Tove Filtenborg Tvedskov, consultant, DMSc, PhD, associate professor, Department of Breast Surgery, Herlev/Gentofte Hospital and Rigshospitalet, Denmark 
Ilse Vejborg, consultant, Department of Breast radiology, Rigshospitalet, Denmark

 

DMCG

Danish Breast Cancer Group

 

Participating institutions

Department of Breast Surgery, Herlev/Gentofte Hospital, Denmark
Department of Breast Surgery, Rigshospitalet, Denmark
Department of Breast radiology, Herlev-Gentofte Hospital, Denmark
Department of Breast radiology, Rigshospitalet, Denmark

 

Status: Pending

WP 2.15: Non-Invasive Diagnostics of Small Renal Masses (NISar)

WP leader

Lars Lund, Chair of DaRenCa, Professor and head of research, DmSci, FCS (HK), Department of Urology, Odense University hospital and University of Southern Denmark

 

DMCG

Danish Renal Cancer Group

 

Participating institutions

Department of Urology at Odense University Hospital, Denmark
Department of Urology at Roskilde University Hospital, Denmark
Department of Urology, Aalborg University Hospital, Denmark
Department of Urology, Vejle Hospital, Denmark
Department of Urology, Southwest Jutland Hospital, Denmark
Peter Clark, Professor, Chair of Department of Urology, Levine Cancer Institute, NC, USA
Maher Albitar, Director, Genomic Testing Cooperative, LCA.,Irvine, CA, USA

 

Status: Pending

WP leader

Marie Louise Bønnelykke-Behrndtz, Department Plastic- and Reconstructive Surgery, Aarhus University Hospital and Aalborg University Hospital, Denmark

 

DMCG

Danish Melanoma Group

 

Participating institutions

National collaboration from all Danish melanoma centers

 

Status: Recruiting

WP 2.17: Applying robot-guided laser osteotomies in malignant bone tumor resection and introducing interlocking osteotomies

WP leader

Thomas Baad-Hansen MD, PhD, Department of Orthopedic oncology, Aarhus University Hospital, Denmark

 

DMCG

Danish Sarcoma Group

 

Participating institutions

Department of Orthopedic oncology, Rigshospitalet, Copenhagen, Denmark

Department of Dentistry and Oral Health, Aarhus University, Denmark

Department of Orthopedic oncology, Aarhus University Hospital, Denmark

 

Status: Ongoing

WP 2.18: Towards preventing reoperations in breast cancer patients with intraoperative surgical margin assessment using spectral microCT

WP leaders

Trine Tramm, Department of Pathology Aarhus  University Hospital and Department of Clinical Medicine, Aarhus University, Denmark

Jasper Nijkamp, Department of Oncology, Aarhus University Hospital and Department of Clinical Medicine, Aarhus University, Denmark

 

DMCG

Danish Breast Cancer Group

 

Participating institutions

Department of Pathology Aarhus  University Hospital, Denmark

Department of Oncology, Aarhus University Hospital,  Denmark

 

Status: Ongoing

WP 2.19: Oncologic Events After Subcutaneous Mastectomy With Or Without Conservation Of The Nipple-areola Complex

WP leader

Tove Tvedskov, Department of Breast Surgery, Copenhagen University Hospital (Herlev/Gentofte Hospital and Rigshospitalet), Denmark

 

DMCG

Danish Breast Cancer Group

 

Participating institutions

Department of Breast Surgery, Copenhagen University Hospital (Herlev/Gentofte Hospital and Rigshospitalet), Denmark

 

Status: Ongoing

WP 2.20: BARREN

WP leader

Nadja Albertsen, MD, Ph.D., Department of Urology, Aarhus University Hospital, Denmark

 

DMCG

Danish Bladder Cancer Group

 

Participating institutions

Department of Urology,  Herlev and Gentofte Hospital, Denmark

MidtSim, Aarhus University

Department of Urology, Rigshopitalet, Denmark

Department of Sports Science and Clinical Biomedchanics, University of Southern Denmark

Department of Surgery, Aarhus University Hospital, Denmark

Department of Gynecology and Obstetrics, Aarhus University Hospital

 

Status: Recruiting

WP 2.21: What is the effect of lymphovenous anastomoses in the treatment of lower limb lymphedema – a pragmatic, open label, randomized controlled trial

WP leader

Lisbet Rosenkrantz Hölmich, Department of Plastic Surgery, Herlev and Gentofte Hospital, Denmark

 

DMCG

Danish Lymphoma Group

 

Participating institutions

Department of Plastic Surgery, Roskilde Hospital and Academy for Medical Education and Simulation (CAMES), Denmark

Department of Plastic Surgery, Odense University Hospital

Department of Physiotherapy and Occupational Therapy, Herlev and Gentofte Hospital

 

Status: Pending

WP 2.22: Breast reconstruction; the multimodality approach

WP leader

Tine Engberg Damsgard, Department of Plastic Surgery, Vejle Denmark

 

DMCG

Danish Breast Cancer Group

 

Participating institutions

Department of Plastic Surgery, Vejle, Denmark.

Department og Plastic Surgery and Burns Treatment, Rigshospitalet, Denmark.

 

Status: Pending

WP 2.23: Intestinal anastomotic microirculation: a mattter of an objective approach

WP leader

Mai-Britt Worm Ørntoft, Department of Surgery, Gødstrup, Denmark.

 

DMCG

Danish Colon Cancer Cancer Group

 

Participating institutions

Department of  Surgery, Gødstrup, Denmark.

Department of Clinical Medicine, Aarhus University, Denmark.

Department of Surgery, Vejle. Denmark.

 

Status: Pending

CFA3: Survivorship

  • Follow-up, late effects and life after cancer tailored to the patient’s preferences and needs, as well as digital solutions
  • Creating models that address the patient’s needs in a digital patient pathway beyond cancer surgery with focus on quality of life and late effects
  • Including patient reports outcome measures as key indicators and outcome parameters in research

Leader

Peter Christensen, MD, PhD

Professor

Danish Cancer Society National Research Center for survivorship and late adverse effects following pelvic organ cancer, Department of Surgery, Aarhus University Hospital, Denmark

Work Packages

WP 3.1: Patient-led follow-up with the use of digital solutions to increase self-management

WP leader

Therese Juul, Associate Professor, Department of Surgery, Aarhus University, Denmark

 

DMCGs

Danish Colorectal Cancer Group

 

Participating institutions

Department of Surgery, Aarhus University Hospital, Denmark
Department of Surgery, Regional Hospital West Jutland, Denmark
Department of Surgery, Aalborg University Hospital, Denmark 
Department of Surgery, Vejle Hospital, part of Lillebaelt Hospital, Denmark

 

Status: Recruiting

WP 3.2: Key indicators for quality of life and late adverse effects following cancer treatment

WP leader

Peter Christensen, Professor, Danish Cancer Society National Research Center for survivorship and late adverse effect following pelvic organ cancer, Aarhus University Hospital, Denmark, and Department of Surgery, Aarhus University Hospital, Denmark

 

DMCGs

Danish Colorectal Cancer Group
Danish Breast Cancer Group
Danish Bladder Cancer Group
with potential migration into all DMCGs

 

Participating institutions

Danish Cancer Society National Research Center for survivorship and late adverse effect following pelvic organ cancer, Aalborg and Aarhus University Hospitals, Denmark
Danish Breast Cancer Group Center & Clinic for late effects (DCCL), Denmark

Deptartment of Oncology, Rigshospitalet, Denmark

 

Status: Ongoing

WP 3.3: Lost in technology? How to tailor follow-up and equal access to follow-up service

WP leader

Henriette Vind Thaysen, Clinical nurse specialist, Department of Surgery, Aarhus University Hospital, Denmark

 

DMCG

Danish Colorectal Cancer Group

 

Participating institutions

Department of Surgery, Aarhus University Hospital, Denmark
Department of Surgery, Regional Hospital West Jutland, Denmark
Department of Surgery, Aalborg University Hospital, Denmark
Department of Surgery, Danish Colorectal Cancer Centre South, Vejle Hospital, Denmark
Department of Cardio-Thoracic and Vascular Surgery, Aarhus University Hospital, Denmark
Danish Research Center for Equity in Cancer (COMPAS), Region Zealand, Denmark

 

Status: Recruiting

WP 3.4: Monitoring late adverse effect with Patient Reported Outcome Measures (ePROM) in patients operated for lung cancer data through an interactive mobile application

WP leader

Thomas Decker Christensen. Professor, Consultant, MD, DMSc, PhD., Department of Cardio-Thoracic and Vascular Surgery & Department of Clinical Medicine, Aarhus University Hospital, Denmark

 

DMCG

Danish Lung Cancer Group

 

Participating institutions

Department of Plastic and Breast Surgery, Aarhus University Hospital, Denmark
Department of Cardiothoracic Surgery, Copenhagen University Hospital, Rigshospitalet, Denmark
IT development, Central Denmark Region, Denmark
Department of Respiratory Diseases and Allergy, Aarhus University Hospital, Denmark

 

Status: Pending

WP 3.5: The MELAcare study: a randomized controlled trial of a new method for surveillance of melanoma patients

WP leader

Lisbet Rosenkrantz Hölmich, Department of Plastic Surgery, Herlev and Gentofte Hospital, Denmark

 

DMCG

Danish Melanoma Group

 

Participating institutions

Department of Plastic Surgery, Herlev and Gentofte Hospital, Denmark
Psychological Aspects of Cancer, The Danish Cancer Society Research Center, Denmark
Department of Oncology, Rigshospitalet, Denmark
Danish Center for Health Economics, University of Southern Denmark, Denmark

 

Status: Data analysis

WP 3.6: Implementation of patient reported outcomes in melanoma treatment: Optimization of recognition and treatment of adverse effects in melanoma treatment

WP leader

Lisbet Rosenkrantz Hölmich, Dept. of Plastic Surgery, Herlev and Gentofte Hospital, Denmark

 

DMCG

Danish Melanoma Group

 

Participating institutions

Department of Plastic Surgery, Herlev and Gentofte Hospital, Denmark
Psychological Aspects of Cancer, The Danish Cancer Society Research Center, Denmark
The Danish Clinical Quality Program– National Clinical Registries (RKKP), Frederiksberg Hospital, Denmark

 

Status: Pending

WP 3.7: CONQUER: Late effects impact on Quality of Life after treatment for bladder cancer

WP leader

Jørgen Bjerggaard Jensen, Professor, DMSc, MD, Department of Urology, Aarhus University Hospital, Denmark

 

DMCG

Danish Bladder Cancer Group

 

Participating institutions

Department of Urology, Aarhus University Hospital, Denmark
Department of Surgery, Aarhus University Hospital, Denmark
Department of Oncology, Rigshospitalet, Denmark

 

Status: Data analysis

WP 3.8: DaVulvaRec: Danish Vulva Cancer Recurrence Study

WP leader

Pernille T. Jensen, Professor, Department Gynecology, Aarhus University Hospital and Aarhus University, Denmark

 

DMCG

Danish Gynaecological Cancer Group

Participating institutions

 

Department of Gynecology, Aarhus University Hospital, Denmark
Department of Gynecology, Rigshospitalet, Denmark
Department of Pathology, Aarhus University Hospital, Denmark
Department of Molecular Medicine, Aarhus University, Denmark

 

Status: Recruiting

WP 3.9: Can a biomarker-based follow-up regimen improve quality of life in patients with stage I and low-risk stage II colorectal cancer compared to standard follow-up?

WP leader

Ole Thorlacius Ussing, Professor, Dept. of Surgery, Aalborg University Hospital, Denmark

 

DMCG

Danish Colorectal Cancer Group

 

Participating institutions

This WP relies on the established framework of the IMPROVE-IT2 trial. Surgical centres at Aalborg, Hjørring, Herning, Viborg, Randers, Aarhus, Horsens, Odense, Svendborg, Herlev, Bispebjerg, Slagelse, and Køge are expected to participate.
ctDNA center and Department of Molecular Medicine, Aarhus University Hospital, Denmark
Regionernes Bio- and Genom Biobank, Denmark
Danish Center for Health Economics, University of Southern Denmark, Denmark

 

Status: Incorporated into WP 3.17

WP 3.10: A national prospective observational study of Circulating tumour DNA, exosomes and Quality of life in Sarcomas

WP leader

Ninna Aggerholm-Pedersen, Clinical Oncologist, MSc, PhD, associate professor, Sarcoma Center Aarhus University Hospital, Department of Oncology, Aarhus University Hospital, Denmark

 

DMCG

Danish Sarcoma Group

 

Participating institutions

Sarcoma center, Aarhus University Hospital, Denmark
Sarcoma Center, Herlev-Gentofte Hospital, Denmark
Department of Surgery, Aarhus University Hospital, Denmark
Department of Orthopedic surgery, Aarhus University Hospital, Denmark
Department of Orthopedic surgery, Rigshospitalet, Copenhagen, Denmark
Department of Oncology, Aarhus University Hospital, Denmark
Department of Oncology, Herlev-Gentofte Hospital, Denmark

 

Status: Recruiting

WP 3.11: Circulating tumor DNA for early detection of recurrence and risk-stratification in melanoma

WP leader

Lisbet Rosenkrantz Hölmich, Professor, DMSc, Department of Plastic Surgery, Herlev and Gentofte Hospital, Denmark

 

DMCG

Danish Melanoma Group

 

Participating institutions

Department of Plastic Surgery, Herlev and Gentofte Hospital, Denmark
Department of Plastic Surgery, Rigshospitalet, Denmark
Department of Plastic Surgery, Zealand University Hospital, Denmark
Department of Plastic Surgery, Aarhus University Hospital, Denmark

 

Status: Data analysis

WP 3.12: Venous thromboembolism in patients with primary lung cancer: Integrating information strategies to promote patient empowerment

WP leader

Thomas Decker Christensen. Professor, Consultant, MD, DMSc, PhD., Department of Cardio-Thoracic and Vascular Surgery & Department of Clinical Medicine, Aarhus University Hospital Denmark

 

DMCG

Danish Lung Cancer Group

 

Participating institutions

Department of Cardiothoracic and Vascular Surgery, Aarhus University Hospital, Department of Clinical Medicine, Aarhus University, Denmark

Danish Center for Health Services Research, Aalborg University & Aalborg University Hospital, Denmark

Department of Clinical Medicine, Aalborg University & Aalborg University Hospital, Denmark

 

Status: Recruiting

WP 3.13: Early Rehabilitation with a Vacuum Erectile Device in Patients Undergoing Nerve-sparing Robotic‑assisted Radical Prostatectomy A Randomized Trial

WP leader

Mads Hvid Aaberg Poulsen, consultant, associate professor, Department for Urology, Odense University Hospital, Denmark

 

DMCG

Danish Prostate Cancer Group

 

Participating institutions

Department for Urology, Odense University Hospital, Denmark

Department of Urology, Herlev/Gentofte Hopsital and Department of Clinical Medicine, University of Copenhagen, Denmark

 

Status: Pending

WP 3.14: CIRCPAC: Implementing non-invasive circulating tumor DNA and circular DNA analysis in patients with localized pancreatic cancer to optimize the pre- and postoperative treatment: predicting recurrence and survival and changing prognosis over time

WP leader

Claus Lindbjerg Andersen, Department of Molecular Medicine, Aarhus University Hospital, Denmark

 

DMCG

Danish Pancreatic Cancer Group

 

Participating institutions

Department of Oncology, Herlev and Gentofte Hospital, Copenhagen University Hospital, Denmark

Department of Molecular Medicine, Aarhus University Hospital, Denmark

Department of Pathology, Odense University Hospital, Denmark

Department of Biology, University of Copenhagen, Denmark

Department of Surgery, Odense Pancreas Center (OPAC), Odense University Hospital, Denmark

 

Status: Recruiting

WP 3.15: Empowering breast cancer patients to assess and address their breast cosmetic outcome after breast conserving therapy

WP leader

Jasper Nijkamp, Department of Oncology, Aarhus University Hospital and Department of Clinical Medicine, Aarhus University, Denmark

 

DMCG

Danish Breast Cancer Group

 

Participating institutions 

Department of Plastic and Reconstructive Surgery, Odense University Hospital, Odense, and University Hospital of Southern Denmark, Vejle, Department of Regional Health Research, University of Southern Denmark, Denmark

Department of Experimental Clinical Oncology, Danish Centre for Particle Therapy, Department of Oncology, Aarhus University Hospital, Denmark

Dept. Oncology, Aarhus University Hospital and Department of Psychology and Behavioural Science, Aarhus University, Denmark

Software Engineering & Computing Systems Section at the Department of Electrical and Computer Engineering, Aarhus University, Aarhus, Denmark

 

Status: Ongoing

WP 3.17: RESPONSE: coloRectal cancEr Survivors’ follow-uP care – nOw digital and Need-baSEd. A national interventional trial for stage I and II patients

WP leader

Mai-Britt Worm Ørntoft, Department of Molecular Medicine, Aarhus University Hospital, Denmark, and Department of Surgery, Regional Hospital West Jutland, Denmark

 

DMCG

Danish Colorectal Cancer Group

 

Participating institutions 

Department of Molecular Medicine, Aarhus University Hospital, Denmark 

Department of Surgery, Aarhus University Hospital, Denmark
Department of Surgery, Regional Hospital West Jutland, Denmark
Department of Surgery, Aalborg University Hospital, Denmark 
Department of Surgery, Vejle Hospital, part of Lillebaelt Hospital, Denmark

Danish Cancer Society National Research Center for survivorship and late adverse effect following pelvic organ cancer, Aarhus University Hospital, Denmark

ACROBATIC – Danish Research Center for Cancer Surgery

 

Status: Expected to start June 2024